XBI ETF

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Showing top 20 of 157 holdings— Unlock all holdings(as of Mar 31, 2026)
#Ticker ↕Name ↕Weight ↓Shares ↕Mkt Value ↕Share ChgSectorIndustry
1APLSApellis Pharmaceuticals Inc1.83%3,562,418$143.32M••••••••••••••••••••••
2ALKS:IEAlkermes Plc1.43%-$111.91M••••••••••••••••••••••
3MDGLMadrigal Pharmaceuticals Inc1.39%207,921$108.84M••••••••••••••••••••••
4TGTXTg Therapeutics Inc Common Stock1.36%3,195,226$106.15M••••••••••••••••••••••
5INSMInsmed Inc1.34%641,246$104.86M••••••••••••••••••••••
6SRRKScholar Rock Holding Corp1.29%2,061,330$101.33M••••••••••••••••••••••
7ARWRArrowhead Pharmaceuticals Inc1.23%1,531,432$96.02M••••••••••••••••••••••
8SMMTSummit Therapeutics Inccommon Stock1.23%5,082,354$96.36M••••••••••••••••••••••
9PRAXPraxis Precision Medicines Inc Common Stock Usd.00011.22%295,929$95.35M••••••••••••••••••••••
10PTGXProtagonist Therapeutics Inc1.22%903,980$95.28M••••••••••••••••••••••
11NUVLNuvalent1.20%913,745$93.61M••••••••••••••••••••••
12TVTXTravere Therapeutics Inc1.20%3,168,992$94.15M••••••••••••••••••••••
13TWSTTwist Bioscience Corp.1.20%1,972,792$93.75M••••••••••••••••••••••
14CYTKCytokinetics1.19%1,408,365$92.83M••••••••••••••••••••••
15EXELExelixis Inc1.19%2,180,741$93.53M••••••••••••••••••••••
16PTCTPtc Therapeutics Inc1.19%1,362,486$92.83M••••••••••••••••••••••
17UTHRUnited Therapeutics Corp1.19%156,569$92.84M••••••••••••••••••••••
18BBIOBridgebio Pharma Inc1.18%1,245,145$92.46M••••••••••••••••••••••
19KYMRKymera Therapeutics Inccommon Stock1.18%1,109,105$92.38M••••••••••••••••••••••
20MIRMMirum Pharmaceuticals Inc1.17%989,867$91.44M••••••••••••••••••••••
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XBI ETF All Holdings

XBI holdings total 157 positions. The top 10 holdings account for 13.5% of the fund, led by Apellis Pharmaceuticals Inc at 1.8%, Alkermes Plc at 1.4%, Madrigal Pharmaceuticals Inc at 1.4%.

XBI portfolio concentration is well-diversified, with the top 10 representing 13.5% of total assets. The largest sector exposure is Health Care at 93.9%.

XBI sector allocation provides a detailed breakdown. XBI overlap tool shows how holdings compare to other funds in your portfolio.

XBI ETF Holdings

157 of 157 holdings

  • 1

    Apellis Pharmaceuticals Inc

    APLSHealth Care
    1.83%
  • 2

    Alkermes Plc

    ALKS:IEHealth Care
    1.43%
  • 3

    Madrigal Pharmaceuticals Inc

    MDGLHealth Care
    1.39%
  • 4

    Tg Therapeutics Inc Common Stock

    TGTXHealth Care
    1.36%
  • 5

    Insmed Inc

    INSMHealth Care
    1.34%
  • 6

    Scholar Rock Holding Corp

    SRRKHealth Care
    1.29%
  • 7

    Arrowhead Pharmaceuticals Inc

    ARWRHealth Care
    1.23%
  • 8

    Summit Therapeutics Inccommon Stock

    SMMTHealth Care
    1.23%
  • 9

    Praxis Precision Medicines Inc Common Stock Usd.0001

    PRAXHealth Care
    1.22%
  • 10

    Protagonist Therapeutics Inc

    PTGXHealth Care
    1.22%
  • 11

    Nuvalent

    NUVLHealth Care
    1.20%
  • 12

    Travere Therapeutics Inc

    TVTXHealth Care
    1.20%
  • 13

    Twist Bioscience Corp.

    TWSTHealth Care
    1.20%
  • 14

    Cytokinetics

    CYTKHealth Care
    1.19%
  • 15

    Exelixis Inc

    EXELHealth Care
    1.19%
  • 16

    Ptc Therapeutics Inc

    PTCTHealth Care
    1.19%
  • 17

    United Therapeutics Corp

    UTHRHealth Care
    1.19%
  • 18

    Bridgebio Pharma Inc

    BBIOHealth Care
    1.18%
  • 19

    Kymera Therapeutics Inccommon Stock

    KYMRHealth Care
    1.18%
  • 20

    Mirum Pharmaceuticals Inc

    MIRMHealth Care
    1.17%
  • 21

    Natera Inc

    NTRAHealth Care
    1.17%
  • 22

    Alnylam Pharmace

    ALNYHealth Care
    1.16%
  • 23

    Neurocrine Bioscienc

    NBIXHealth Care
    1.16%
  • 24

    Krystal Biotech Inc

    KRYSHealth Care
    1.15%
  • 25

    Vaxcyte Inc

    PCVXHealth Care
    1.15%
  • 26

    Amicus Therapeutics Inc

    FOLDHealth Care
    1.14%
  • 27

    Arcellx, Inc.

    ACLXHealth Care
    1.14%
  • 28

    Cg Oncology Inc

    CGONHealth Care
    1.14%
  • 29

    Ionis Pharmaceuticals Inc

    IONSHealth Care
    1.14%
  • 30

    Regeneron Pharmaceuticals

    REGNUnknown
    1.14%
  • 31

    Incyte Corp

    INCYUnknown
    1.13%
  • 32

    Revolution Medicines Inc Ser C Pc Pp

    RVMDHealth Care
    1.12%
  • 33

    Arcutis Biotherapeutics Inc

    ARQTHealth Care
    1.11%
  • 34

    Cogent Biosciences Inc

    COGTHealth Care
    1.11%
  • 35

    Halozyme Therapeutics Inc

    HALOHealth Care
    1.11%
  • 36

    Rhythm Pharmaceuticals Inc

    RYTMHealth Care
    1.11%
  • 37

    Crispr Therapeutics Ag

    CRSP:SMHealth Care
    1.11%
  • 38

    Celcuity Inc Common Stock Usd 0.001

    CELCHealth Care
    1.10%
  • 39

    Biogen Inc. Com

    BIIBHealth Care
    1.09%
  • 40

    Gilead Sciences Inc

    GILDHealth Care
    1.09%
  • 41

    Abbvie Inc

    ABBVHealth Care
    1.07%
  • 42

    Biomarin Pharmaceutical Inc.

    BMRNHealth Care
    1.07%
  • 43

    Roivant Sciences Ltd

    ROIVHealth Care
    1.07%
  • 44

    Amgen Inc.

    AMGNHealth Care
    1.06%
  • 45

    Beam Therapeutics Inc

    BEAMHealth Care
    1.05%
  • 46

    Erasca Inc

    ERASHealth Care
    1.05%
  • 47

    Viking Therapeutics Inc Com

    VKTXHealth Care
    1.04%
  • 48

    Vera Therapeutics Inc Class A

    VERAHealth Care
    1.03%
  • 49

    Nvaesrtex Pharmaceuticals Inc

    VRTXHealth Care
    1.03%
  • 50

    Acadia Pharmaceuticals Inc Common Stock Usd 0.0001

    ACADHealth Care
    1.02%
  • 51

    Moderna therapeutics

    MRNAHealth Care
    1.01%
  • 52

    Immunitybio Inc

    IBRXHealth Care
    0.98%
  • 53

    Sarepta Therapeutics Inc

    SRPTHealth Care
    0.90%
  • 54

    Ultragenyx Pharmaceutical Inc

    RAREHealth Care
    0.89%
  • 55

    Agios Pharmaceuticals Inc

    AGIOHealth Care
    0.88%
  • 56

    Disc Medicine Inc

    IRONHealth Care
    0.88%
  • 57

    Immunome Inc

    IMNMHealth Care
    0.88%
  • 58

    Immunovant Inc

    IMVTHealth Care
    0.86%
  • 59

    Veracyte, Inc.

    VCYTHealth Care
    0.85%
  • 60

    Biocryst Pharmaceuticals

    BCRXHealth Care
    0.83%
  • 61

    Dyne Therapeutics Inc

    DYNHealth Care
    0.83%
  • 62

    Kodiak Sciences Inc

    KODHealth Care
    0.77%
  • 63

    Catalyst Partners Acquisition Corp Ieu

    CPARUHealth Care
    0.75%
  • 64

    Grail Inc Common Stock Usd

    GRALHealth Care
    0.75%
  • 65

    Syndax Pharmaceuticals Inc

    SNDXHealth Care
    0.75%
  • 66

    Denali Therapeutics Inc

    DNLIHealth Care
    0.74%
  • 67

    Soleno Therapeutics Inc

    SLNOHealth Care
    0.74%
  • 68

    Ideaya Biosciences Inc

    IDYAHealth Care
    0.71%
  • 69

    Spyre Therapeutics Inc

    SYREHealth Care
    0.70%
  • 70

    Recursion Pharmaceuticals Inc

    RXRXHealth Care
    0.68%
  • 71

    Viridian Therapeutics Inc

    VRDNHealth Care
    0.68%
  • 72

    Intellia Therapeutics Inc

    NTLAHealth Care
    0.67%
  • 73

    Dianthus Therapeutics Inc

    DNTHUnknown
    0.66%
  • 74

    Ardelyx Inc

    ARDXHealth Care
    0.63%
  • 75

    Arcus Biosciences Inc

    RCUSHealth Care
    0.63%
  • 76

    Mineralys Therapeutics Inc

    MLYSHealth Care
    0.63%
  • 77

    Adma Biologics Inc Com

    ADMAHealth Care
    0.60%
  • 78

    Nurix Therapeutics Inc.

    NRIXHealth Care
    0.58%
  • 79

    Tango Therapeutics Inc.

    TNGXHealth Care
    0.56%
  • 80

    Celldex Therapeutics Inc

    CLDXHealth Care
    0.51%
  • 81

    Oruka Therapeutics Inc Orka

    ORKAHealth Care
    0.51%
  • 82

    Novavax Inc

    NVAXHealth Care
    0.50%
  • 83

    Olema Pharmaceuticals Inc

    OLMAHealth Care
    0.50%
  • 84

    Vericel Corp

    VCELHealth Care
    0.49%
  • 85

    Biohaven Ltd

    BHVNUnknown
    0.49%
  • 86

    Stoke Therapeuti

    STOKHealth Care
    0.48%
  • 87

    Capricor Therapeutics Inc

    CAPRHealth Care
    0.47%
  • 88

    Monte Rosa Therapeutics Inc.

    GLUEHealth Care
    0.45%
  • 89

    Palvella Therapeutics Inc

    PVLAHealth Care
    0.44%
  • 90

    Corvus Pharmaceuticals Inc

    CRVSHealth Care
    0.41%
  • 91

    Relay Therapeutics Inc

    RLAYHealth Care
    0.41%
  • 92

    Anaptysbio Inc

    ANABHealth Care
    0.39%
  • 93

    Iovance Biotherapeutics Inc

    IOVAHealth Care
    0.38%
  • 94

    Uniqure Nv

    QURE:ASHealth Care
    0.38%
  • 95

    Geron Corp

    GERNHealth Care
    0.37%
  • 96

    Mannkind Corp.

    MNKDHealth Care
    0.37%
  • 97

    Caredx Inc

    CDNAHealth Care
    0.35%
  • 98

    Tyra Biosciences Inc

    TYRAHealth Care
    0.34%
  • 99

    Precigen Inc Common Stock

    PGENHealth Care
    0.32%
  • 100

    Taysha Gene Therapies Inc

    TSHAHealth Care
    0.32%
  • 101

    Day One Biopharmaceuticals I

    DAWNUnknown
    0.32%
  • 102

    Vir Biotechnology Inc.

    VIRHealth Care
    0.30%
  • 103

    Janux Therapeutics Inc

    JANXHealth Care
    0.28%
  • 104

    Kalvista Pharmaceuticals Inc

    KALVHealth Care
    0.28%
  • 105

    Kura Oncology Inc

    KURAHealth Care
    0.28%
  • 106

    Annexon Inc

    ANNXHealth Care
    0.27%
  • 107

    COMPASS THERAPEUTICS INC

    CMPXHealth Care
    0.27%
  • 108

    Cytomx Therapeutics Inc 144A

    CTMXHealth Care
    0.27%
  • 109

    Sana Biotechnology Inc

    SANAHealth Care
    0.27%
  • 110

    Savara Inc

    SVRAHealth Care
    0.27%
  • 111

    Rigel Pharmaceuticals Inc

    RIGLUnknown
    0.26%
  • 112

    Sellas Life Sciences Group Inc.

    SLSHealth Care
    0.26%
  • 113

    Zenas Biopharma Inc

    ZBIOHealth Care
    0.25%
  • 114

    Cullinan Oncology Inc

    CGEMHealth Care
    0.24%
  • 115

    Xencor Inc

    XNCRHealth Care
    0.24%
  • 116

    Ars Pharmaceuticals, Inc.

    SPRYUnknown
    0.24%
  • 117

    Arrivent Biopharma Inc

    AVBPHealth Care
    0.23%
  • 118

    Sionna Therapeutics Inc

    SIONHealth Care
    0.23%
  • 119

    Oric Pharmaceuticals Inc

    ORICHealth Care
    0.22%
  • 120

    Replimune Group Inc Com

    REPLHealth Care
    0.22%
  • 121

    Vor Biopharma Inc

    VORHealth Care
    0.22%
  • 122

    Ironwood Pharmaceuticals Inc

    IRWDHealth Care
    0.21%
  • 123

    Absci Corp

    ABSIHealth Care
    0.19%
  • 124

    Bcax Bicara Therapeutics Inc.

    BCAXHealth Care
    0.19%
  • 125

    Apogee Therapeutics Inc

    APGEHealth Care
    0.18%
  • 126

    Allogene Therapeutics Inc

    APGEHealth Care
    0.18%
  • 127

    Altimmune Inc

    ALTHealth Care
    0.18%
  • 128

    Emergent Biosolutions Inc

    EBSHealth Care
    0.18%
  • 129

    Prime Medicine Inc Common Stock USD.00001

    PRMEHealth Care
    0.18%
  • 130

    4d Molecular Therapeutics Inc.

    FDMTHealth Care
    0.17%
  • 131

    Hypera Sa

    HYPE3:BVUnknown
    0.17%
  • 132

    Regenxbio Inc

    RGNXHealth Care
    0.16%
  • 133

    Vanda Pharmaceuticals Inc

    VNDAHealth Care
    0.16%
  • 134

    Verastem Inc

    VSTMUnknown
    0.15%
  • 135

    Arbutus Biopharma Corp.

    ABUSHealth Care
    0.14%
  • 136

    Lexeo Therapeutics Inc - Series B

    LEXOHealth Care
    0.14%
  • 137

    Myriad Genetics Inc

    MYGNHealth Care
    0.13%
  • 138

    Ocugen Inc.

    OCGNHealth Care
    0.13%
  • 139

    Rocket Pharmaceuticals Inc

    RCKTHealth Care
    0.13%
  • 140

    Prothena Corp

    PRTA:IEHealth Care
    0.13%
  • 141

    Mimedx Group Inc Com

    MDXGHealth Care
    0.12%
  • 142

    Akebia Therapeutics Inc

    AKBAHealth Care
    0.11%
  • 143

    Anavex Life Sciences Corp Common Stock Usd 0.001

    AVXLHealth Care
    0.11%
  • 144

    Invivyd Inc

    IVVDHealth Care
    0.10%
  • 145

    Perspective Ther

    CATXHealth Care
    0.10%
  • 146

    Contra Metsera Inc

    Other
    0.09%
  • 147

    Ssi Us Gov Money Market Class

    GVMXXUnknown
    0.06%
  • 148

    Damora Therapeutics Inc

    DMRAUnknown
    0.03%
  • 149

    Contra Akero Therapeut

    Other
    0.02%
  • 150

    Inhibrx Biosciences Inc

    INBXHealth Care
    0.01%
  • 151

    Contra Inhibrx Inc Common Stock

    INBXUnknown
    0.01%
  • 152

    Ping An Insu Ran Ce Group Co. Of C Hin A Ltd.

    601318:SHHealth Care
    0.01%
  • 153

    Contra Verve Therapeut

    Other
    0.01%
  • 154

    Omniab Inc 12.5 Earnout

    OABIHealth Care
    0.00%
  • 155

    Omniab Inc 15.00 Earnout

    OABIHealth Care
    0.00%
  • 156

    Contra Blueprint Medic

    Other
    0.00%
  • 157

    US Dollar

    Other
    0.00%