Protagonist Therapeutics, Inc., a biopharmaceutical company, develops peptide therapeutics for hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing Rusfertide, an injectable mimetic of hepcidin that is in phase 3 clinical trials for the treatment of polycythemia vera; Icotrokinra, an orally delivered investigational drug which is in phase 3 clinical trials indicated to block biological pathways targeted by marketed injectable antibody drugs; and PN-943, an orally delivered, gut-restricted alpha 4 beta 7 specific integrin antagonist completed a phase 2 clinical trials in patients with moderate to severe ulcerative colitis. The company also develops IL-17 oral peptide antagonist PN-88,1 an oral metabolic/obesity peptide program, and an oral hepcidin mimetic/ferroportin blocker that is in pre-clinical stage. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.

Period	PE Ratio
2016-12-31	N/A
2017-12-31	N/A
2018-12-31	N/A
2019-12-31	-37.87
2020-12-31	-58.78
2021-12-31	-41.65
2022-12-31	-43.41
2023-12-31	-81.19
2024-12-31	25.25
2025-12-31	-55.05

	A	B	C	D
1	Symbol	Price	Change	Volume
2	PTGX	$112.86	+1.27%	1.53M
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